FOXO3 and non-small cell lung carcinoma: However, Li et al. indicated that circ_0002483 overexpression significantly inhibited NSCLC cell proliferation and invasion in vitro and in vivo, and enhanced NSCLC sensitivity to taxol by sponging miR-182-5p to release the inhibition on GRB2, FOXO1 and FOXO3 mRNAs (243).