MTHFR and Rare hereditary thrombophilia: The hemato-oncologist was consulted to workup the thrombophilia disorders that included testing for factor V Leiden, prothrombin mutation and MTHFR as well as antiphospholipid panel, protein C and S, antithrombin 3, factor II, factor XIII, plasminogen activator inhibitor-1 mutation and annexin A5 antibodies.