Mohammadpour et al showed that increased β2-AR signalling in mice resulted in increased growth of 4T1 and AT-3 mammary carcinomas and an increase in the accumulation and immunosuppressive function of MDSCs (Mohammadpour 2019), and Mundy-Bosse et al found that patients reporting higher levels of stress had increased levels of MDSCs that correlated with increased salivary cortisol levels (Mundy-Bosse 2011). The gene discussed is ADRB2; the disease is breast carcinoma.