Moreover, the TGF‐β1 found in EVs in GC patients has been associated with pathological stages and LN metastasis, thus, signifying the importance of EV‐associated TGF‐β1 as a predictive parameter for LN metastasis in GC patients (Yen et al., 2017) (Figure 1d). The gene discussed is TGFB1; the disease is gastric cancer.