Consistently with differential expression analysis results, eight lncRNAs including ATP11A-AS1, ITPK1-AS1, ANO1-AS2, CRNDE, MALAT1, CACNA1C-IT3, PWRN1, and WT1-AS were significantly upregulated in ALL bone marrow, indicating that these abnormally expressed lncRNAs could be involved in the development of ALL. Here, MALAT1 is linked to acute lymphoblastic leukemia.