The authors defined wild-type homozygotes as A, heterozygotes and mutant homozygotes as B. Among analyses of BPI, TLR and LBP, LBP A + BPI A + TLR A was associated with a high risk of sepsis (p=0.005), LBP B + BPI A + TLR A was a high-risk combination for sepsis with severe condition (p=0.034) (49). The gene discussed is LBP; the disease is Sepsis.