Pla2g2d also known as the “resolving sPLA2” ameliorates inflammation through mobilizing proresolving lipid mediators and reducing Th1 cytokine production (Miki et al., 2013), while Pla2g2a can be stimulated by IL-6 production and protects against Gram-positive bacterial infection (Nevalainen et al., 2008). This evidence concerns the gene PLA2G2A and gram-positive bacterial infections.