In addition, the interaction between treatment with JPE and the presence or absence of DM had a statistically significant effect on the activity of antioxidant enzymes (SOD p = 0.002 and CAT p = 0.044) and lipid peroxidation (p = 0.007), demonstrating that JPE could only reduce these parameters when there are alterations induced by DM. Here, SOD1 is linked to diabetes mellitus.