In an antitumor tumor-burdened mice observation experiment, the tumor sizes of the normal saline, free UA, UA liposome, UA folate liposome targeting, and FA-UA/siRNA-L groups were 2,254, 1,300, 1,156, 753, and 318 mm3, respectively, which suggests that FA targeted liposomes can significantly enhance the UA anti-cancer effect, and UA and Bmi1 siRNA have some synergistic antitumor effects (Li W. et al., 2019). Here, BMI1 is linked to cancer.