MMP2 and hepatocellular carcinoma: The aqueous extract of Patrinae Herba which most probably contains polysaccharidic compounds, showed anti-proliferative, anti-metastatic properties in hepatocellular carcinoma cell lines, via up-regulating the lncHTR2A-AS1 and subsequently influencing the concentration of several proteins–MMP2, P21, caspase 3, E-Cadherin (Guan et al., 2020).