AGT and cardiac hypertrophy: Oxidative stress, which has a critical link with the development of cardiac hypertrophy and heart failure, can reportedly be inhibited by oridonin via mitigating pressure overload-induced cardiac hypertrophy and fibrosis, preserving heart function, enhancing myocardial autophagy in pressure-overloaded hearts and angiotensin II-stimulated cardiomyocytes (Xu M. et al., 2019).