However, 2 weeks after the transduced cells were injected SQ into mice (103 to 2 × 104 transduced cells in 100 μL of 50% Matrigel/site), the nascent tumours already evident by that time showed strong increases in YB-1 expression by IHC as compared to simultaneously stained samples of the original breast tissue samples from which the transduced cells had been isolated (Fig. 4B and Appendix Fig. S6C). Here, YBX1 is linked to neoplasm.