A partial correlation between metabolic concentrations and MADRS score corrected for age, BMI and CRP further confirmed that LDL2 (Rho = −0.192, p = 0.046), LDL2-cholesterol (Rho = −0.190, p = 0.049), LDL2-phospholipids (Rho = −0.202, p = 0.036) and LDL2-apolipoprotein B (Rho = −0.192, p = 0.046) were significantly inversely correlated with depression severity independently of the covariates. This evidence concerns the gene APOB and major depressive disorder.