The autoantibodies against retinal proteins, such as recoverin, arrestin, transducin, rhodopsin, tubby-like protein 1 (TULP1), carbonic anhydrase II (CAII), heat shock protein 27 (HSP27), HSP60, Rab6, and collapsin response mediator protein (CRMP), can be detected in the AIR patient sera4,8. The gene discussed is CA2; the disease is autoimmune retinopathy.