As showed in Fig. 6a, b, GLT8D2 levels in 12 freshly collected clinical ovarian cancer samples with chemotherapy were positively correlated with phosphatase levels of FRS2a (Tyr196) (r = 0.86, P < 0.001) and AKT (Ser473) (r = 0.912, P < 0.001). Here, FRS2 is linked to ovarian cancer.