Nude mice were subcutaneously inoculated with SKOV3-Scr, SKOV3-GLT8D2 –shRNA#1, SKOV3-GLT8D2 –shRNA#2 respectively, mouse were treated with CDDP or vehicle when the treatment with drugs started as soon as the tumor became palpable. This evidence concerns the gene GLT8D2 and neoplasm.