DNM2 mediates the Platelet Derived Growth Factor Receptor α (PDGFRα)-stimulated growth and invasion of glioblastoma cells through the formation of a Src-phosphorylated DNM2-PDGFRα-tyrosine-protein phosphatase non-receptor type 11 (SHP2) complex [60]. Here, PTPN11 is linked to glioblastoma.