DNM2 and familial pancreatic carcinoma: The benefit of pharmacological inhibitors [75, 84, 85, 89] or DNM2 mRNA silencing on cell invasion in prostate, lung, bladder, and pancreatic cancer cells is provided through an impact on actin dynamics and formation of the actin-based protrusions (lamellipodia, filopodia, and invadopodia) and/or stabilizing focal adhesion which impede invasive behaviour [36, 42, 43, 57, 58, 61, 62, 89].