AKT1 and neoplasm: The results of RT-qPCR and Western blot analysis (Fig. 7C, D) showed a decline of the expression of miR-182-5p in tumor tissues in response to treatment with the EVs + miR-182-5p inhibitor while the expression of CMTM7 was increased, along with decreased expression of VEGF and EGFR and AKT phosphorylation levels.