From our FFPE-tissue collection, we selected four types of gliomas for which both solid material of TCR and CUSA were available from the same patients: an oligodendroglioma, IDH-mutant and 1p/19q-codeleted (OII), an astrocytoma, IDH-wildtype (AIII), and two GBs, IDH-wildtype; to distinguish these GBs throughout this work, one of them will be referred hereafter as GS (for gliosarcoma). This evidence concerns the gene IDH1 and central nervous system cancer.