Based on Loess plots and analyses using indicator variables among ART users once duration reached 2 years, prevalent HTN did not increase further with duration on ART after adjusting for age; meanwhile participants with HTN exhibited higher CD4 counts than those without HTN [409 cells/mm3 (231 598) vs 359 (171, 558), p<0.001], Table 1. The gene discussed is CD4; the disease is hypertensive disorder.