The pattern on biopsy has been classified in two ways when full house immunofluorescent staining is seen: as (1) lupus-like glomerulonephritis, in the case where systemic signs of lupus and lupus autoantibodies develop in the future [12], or (2) idiopathic full house nephropathy (positivity in IgG, IgM, IgA, C1q, and C3) in the case where patients never develop extra-renal signs of lupus [10]. This evidence concerns the gene C3 and systemic lupus erythematosus.