(A-C) Firing rate of individual GnRH-green fluorescent protein (GFP) neurons in brain slices from diestrous females injected in the POA with adeno-associated virus (AAV)-mCherry (A, n=12 from five mice) or AAV-Gq (B, n=10 from five mice, C, n=4 from two mice); slices in C had viral infection of cells with neuronal morphology. Here, GNRH1 is linked to viral infectious disease.