MCL1 and central nervous system cancer: Here, we demonstrated that SD‐36 induces apoptosis involving suppression of Mcl‐1 in human glioma cancer cells since induced ectopic Mcl‐1 expression remarkably attenuated apoptosis induced by SD‐36 in U87 and U251 cells, whereas Mcl‐1 knockdown or inhibition enhanced apoptosis induced by SD‐36 in glioma cells.