Tendon samples from the point of maximal injury in APS treated, saline treated, and normal tendon were analyzed for expression of MMP1, MMP3, MMP13, ADAMTS4, COL1A1, COL3A1, SCX, TNMD, TNC, DCN, and COMP using real time quantitative PCR. The gene discussed is ADAMTS4; the disease is autoimmune polyendocrinopathy.