The ALB (6.22 ± 3.25 × 109/L) and serum Na+ (137.22 ± 6.05 mmol/L) in liver cirrhosis patients with atrial arrhythmia were significantly lower than that in the group without atrial arrhythmia (ALB: 32.56 ± 6.91 g/L, serum Na+: 139.46 ± 4.65 mmol/L). This evidence concerns the gene ALB and cirrhosis of liver.