The WBC (6.22 ± 3.25 × 109/L) and BNP (295.08 ± 308.15 pg/mL) in liver cirrhosis patients with atrial arrhythmia were significantly higher than those in patients without atrial arrhythmia (WBC: 4.59 ± 2.44 × 109/L, BNP: 97.14 ± 142.51 pg/mL). The gene discussed is NPPB; the disease is cirrhosis of liver.