ANGPTL4 and metastatic malignant neoplasm in the lymph nodes: This finding is in accordance with that of Nie et al., who reported that ANGPTL4 was up-regulated in CC samples, and this up-regulation was associated with lymph node metastasis, deep stromal invasion, lympho-vascular space invasion, and advanced tumor stage, as well as poor OS and DFS (Nie et al., 2019).