We identified and verified that FGD6 was highly expressed in GC tissues relative to para-cancerous tissues, as well as in the GSE63089 dataset of GEO database; the FGD6 expression level was significantly overexpressed in GC tissues as compared to the normal gastric tissues, as verified by qRT-PCR, and its expression level was correlated with clinicopathological parameters and GC patient survival. Here, FGD6 is linked to gastric cancer.