As shown in Figure 7D, monocytes, M1 macrophages, and neutrophil increased in the high CARS expression group, whereas CD8+ T cell, activated NK cell, and gamma delta T cell decreased (P < 0.05), and the heat map visualized the percentage of abundance of tumor-infiltrating immune cells in each sample of low and high CARS group (Figure 7E). This evidence concerns the gene CD8A and neoplasm.