Age did not influence the PDCD1 genotype frequency among patients presenting or not HPV (P = 0.3066), and among patients exhibiting benign injury (P = 0.1692), CIN I (P = 0.5698), CIN II (P = 0.0746) or CIN III (P = 0.7366) compared to women with normal cytomorphological results. The gene discussed is PDCD1; the disease is uterine cervix carcinoma in situ.