Here, we also showed that, as compared to EGCG, kaempferol at high concentrations can further decrease the expression of ABCB1 and ABCC1 in HL60 cells in the long term (5 days), an effect which is consistent with some studies reporting that kaempferol inhibited MDR proteins in some cancer cells (Kitagawa et al., 2005 ▶; Limtrakul et al., 2005 ▶; Nakamura et al., 2005 ▶; Pal and Mitra, 2006 ▶; Chung et al., 2007 ▶; To et al., 2012 ▶; Kuete et al., 2014 ▶). This evidence concerns the gene ABCC1 and cancer.