As regression of microalbuminuria is possible through treatment, microalbuminuria screening is very important to prevent progression to renal failure and to determine cardiovascular disease risk.3,4 Spot urinary albumin/creatinine ratio measurement is performed for screening test.5 Due to the difficulties involved in the collection of 24-hour urine samples, using these samples for screening is not a practical method. This evidence concerns the gene ALB and cardiovascular disorder.