it increases the concentration of GLUT-4 in the cell membrane and increases glucose uptake in skeletal muscles.26-28 Acute exercise increases glucose tolerance, insulin sensitivity and decrease blood glucose levels.29,30 The literature has also shown that acute and moderate-intensity endurance exercise decreases the blood glucose levels.29,30 These are the possible mechanisms in playing sports including cricket leads to decrease in prevalence of prediabetes and T2DM. The gene discussed is INS; the disease is type 2 diabetes mellitus.