CD4 and infection: Some patients would have improved nutritional indicators and infection rates when receiving immune-enhancing additives (such as glutamine, arginine, and omega-3 fatty acids).21 Lorenz et al.22 suggested that compared with patients receiving an isocaloric diet, patients receiving glutamine supplementation had better total lymphocyte count, activated CD4+DR+T helper lymphocyte percentage, lymphocyte response to mitogen in vitro, and normalization rate of IL-2 plasma levels.