Recent results have shown that some miRNAs belonging to the miR-148 family (including miR-152, miR-148B, and miR-148A) can inhibit histocompatibility antigen, class I, G (HLA-G) expression, as well as the occurrence and development of GC (Zhai et al., 2014). The gene discussed is HLA-G; the disease is gastric cancer.