MICA and neoplasm: miRNAs such as miR-20a, miR-10b, miR-25, miR-93, miR-17-5p, miR-433, and miR-106b can promote tumor growth; regulate the expression of genes encoding the major histocompatibility complex class I chain-related proteins A and B; increase tumor angiogenesis, cell proliferation, and invasion; and negatively interfere with natural killer cell-mediated cytotoxicity (Jasinski-Bergner et al., 2014; Xie et al., 2014).