KRT18 is a cytokeratin in epithelial and endothelial cells reported to be aberrantly expressed and regarded as a biomarker and important regulator in many cancers, including GC (Yin et al., 2016; Zhang et al., 2016, 2019a; Bozza et al., 2018; Nagel et al., 2018; Golob-Schwarzl et al., 2019). The gene discussed is KRT18; the disease is cancer.