JNK2 has been reported to be a mediator of cell apoptosis and death (Arbour et al., 2002; Zhong et al., 2007) and also induce cell survival in the contrary (Hochedlinger et al., 2002; Liu et al., 2004), underlining that the functional mechanism of JNK2 in GC needs to be further investigated. This evidence concerns the gene MAPK9 and gastric cancer.