Because NS3 is an intracellular protein, most studies have focused on identifying T-cell immunodominant regions, reporting that epitopes located in the NTPase and helicase of NS3 are the most immunodominant in the cellular response against dengue (52, 53) and that this response towards NS3 is associated with dengue hemorrhagic fever (54). The gene discussed is KRAS; the disease is Dengue hemorrhagic fever.