It should be noted that our co-correlate network analysis in the pairwise comparisons of LTBI/ATB (Figure 1G), ATB/txATB (Figure 2G), and LTBI/txATB (Figure 3G) also highlighted both IgA and IgM related features that highly correlated with the features selected by LASSO/PLSDA models with additional discriminatory potential for the TB disease states studied here. The gene discussed is CD40LG; the disease is tuberculosis.