Patients with < 10% (0-62.1%) Bregs (within CD19+B-cell compartment) had significantly worse OS (21) with levels of serum B cell maturation antigen (sBCMA) are associated with PFS and OS in MM patients; sBCMA > 326.4 ng/mL had inferior PFS and OS (22). This evidence concerns the gene CD19 and Miyoshi myopathy.