Resident lung fibroblasts represent key effector cells in IPF pathogenesis since under the action of TGF-β can proliferate and differentiate into myofibroblasts promoting fibrogenesis and impairing normal alveolar epithelial repair in response to damage (David and Cory, 2017; Chanda et al., 2019). This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.