CD4 and Miyoshi myopathy: Compared to MGUS/SMM patients or healthy individuals, MM patients’ (newly diagnosed, relapsed, relapsed/refractory) BMMC and PBMC had significantly (*p < 0.05) decreased CD4+ Th, but not CD8+ Tc cells (data not shown), as well as increased CD4+ Treg (CD3+CD4+/FOXP3+CD25+) (Fig. 2A).