The tumor lysates induced a greater T-cell response in MM patients’ BMMC (N = 5) than irradiated whole tumor cells, which was enhanced to a greater extent by checkpoint inhibitors (anti-LAG3 > anti-PD1) than by immune agonists (anti-OX40, anti-GITR) (Supplementary Fig. 1). Here, LAG3 is linked to Miyoshi myopathy.