Conversely, known ovarian cancer targets MUC16 and MSLN were not epithelial-restricted and were expressed in both the fibroblast population (12.4% MUC16+, 53.1% MSLN+) and the malignant epithelial cell population (51.3% MUC16+, 78.5% MSLN+) (Supplementary Fig. 1B, C). Here, MSLN is linked to ovarian carcinoma.