PAX8 occupies an intragenic enhancer in the LYPD1 gene locus for LYPD1-expressing ovarian cancer cell lines OVCAR3, KURAMOCHI, and COV318 but not OVCAR4 (Fig. 1C), suggesting that PAX8 might contribute to the transcriptional regulation of LYPD1 expression. This evidence concerns the gene PAX8 and ovarian cancer.