FUS and neuroblastoma: Expression of green fluorescent protein (GFP)-tagged FUS protein with missense mutation FUSR521C or truncation mutant FUSR495X in the neuronal-like neuroblastoma cell line, SH-SY5Y, led to a significant increase in the fluorescence intensity of cytoplasmic FUS (Fig. 1e–k) when compared to FUSWT (Fig. 1a–c,h).