A time-dependent rapid increase in the expression of BCL2, MMP9, E-CADHERIN, AKT, NF-kβ, and SNAIL and a moderate increase in VIMENTIN, C-MYC, CASP, CYCLIN1, SMAD, BAX, CDK4, LYNK1, and MMP2 similar to hallmark cell proliferation and metastasis regulator genes are observed in cancer cells over the coculture time due to platelets. The gene discussed is CDH1; the disease is cancer.