Although the main analysis, using reference ranges for ALT and AST defined in 2014 by the central laboratory, suggested an approximately twofold higher (exposure- and gender-adjusted) probability of transaminase elevations for patients in the INBUILD trial than for patients in the IPF or SENSCIS trials, no significant difference between trials was present in the sensitivity analysis using 2019 updated reference ranges for ALT and AST. This evidence concerns the gene GPT and idiopathic pulmonary fibrosis.