For one thing, although tumor growth in TNBC-bearing mice models, was inhibited by formononetin at the concentration of 80 mg/kg (Supplementary Table 4), along with decreased lncRNA AFAP1-AS1 level and increased miR-545-3p/miR-195 level in the tumor tissues (Supplementary Figure 8), joint effects of formononetin, si-lncRNA AFAP1-AS1 and miR-545-3p/miR-195 mimic on tumor growth in the mice models were not studied. This evidence concerns the gene AFAP1 and neoplasm.