It was also corroborated that doxorubicin-sensitivity of MCF-7 cell line was rescued in the presence of high-level lncRNA Adriamycin Resistance Associated (ARA) [47], while lncRNA Breast Cancer Anti-Estrogen Resistance 4 (BCAR4) functioned to strengthen tamoxifen-resistance of MCF-7 cell line and ZR-75-1 cell line [48]. The gene discussed is BCAR4; the disease is breast carcinoma.