TNF and Sepsis: Meanwhile, Pearson correlation coefficient analysis exhibited that the level of miR-455-5p in NS patients was significantly positively correlated with the levels of WBC, CRP, PCT, NLR, and the levels of inflammatory factors, including IL-6, IL-8, TNF-α, We speculated that the expression level of miR-455-5p was closely related to the degree of inflammatory response in sepsis.