For 3 of the variants (AIRE:c.254A>G [autoimmune polyendocrinopathy], LIPA:c.260G>T [Wolman’s disease], and GNE:c.2228T>C [inclusion body myopathy (HIBM)]), carrier frequency was assayed previously in Mizrahi Jews and found to be similar to the frequencies reported here (Kaback et al., 2010; The Forward Staff, 2014). This evidence concerns the gene LIPA and autoimmune polyendocrinopathy.