In addition, Syrian Jews carried variants that are less frequent in Ashkenazis and implicated in the following autosomal recessive disorders: achromatopsia, congenital adrenal hyperplasia (CYP11B1 gene), Friedreich ataxia, Gaucher disease, inclusion body myopathy, metachromatic leukodystrophy, Niemann–Pick disease, primary hyperoxaluria type 1, retinitis pigmentosa 28, and Ullrich congenital muscular dystrophy type 1. The gene discussed is CYP11B1; the disease is Gaucher disease.