MTOR and atrial fibrillation: Previous researches have shown that oxidative stress and AMPK were upstream mechanisms that regulate necroptosis, and autophagy was linked to necroptosis,though we did not detect any significant change in cardiac oxidative stress between sedentary and exercised AF mice (data not shown), AMPK/mTOR‐mediated autophagy signaling was apparently enhanced in exercised mice compared with sedentary mice (Figure S4).