Moreover, we further found that CELF2 in BRCA and LUSC were moderately to strongly correlated with the main immunosuppressive Th1 and Treg cell marker sets (TBX21 and STAT4; FOXP3 and CCR8) as well as T‐cell exhaustion markers (PD‐1, CTLA‐4 and TIM‐3) within the TME (Tables 2 and 3). This evidence concerns the gene CTLA4 and invasive breast carcinoma.