Of all 143 patients at diagnosis, moderate yet statistically highly significant correlations between anti‐Dsg1 and BSA (Spearman ρ = 0.45, P < 0.001) and between anti‐Dsg3 and OSA (ρ = 0.53, P < 0.001) were found. The gene discussed is DSG1; the disease is obstructive sleep apnea syndrome.