Notably, both Cav-1 expression levels and the VM-forming ability were positively correlated with the presence of cystic tumor (P=0.000 and P=0.028, respectively), WHO grades (P=0.000 for both), and survival at 16-month interval (P=0.007 and P=0.002, respectively) using multivariate analyses. This evidence concerns the gene CAV1 and cystic neoplasm.